Celiac (Coeliac) Disease, also known as celiac sprue, gluten-sensitive enteropathy, and non-tropical sprue, is an inherited autoimmune disorder affecting children and adults. When an individual with Celiac ingests gluten, a protein found in wheat, barley & rye, the lining of the small intestine, known as the “villi” (finger-like projections), become flattened over time. Once the villi become damaged (villous atrophy), they are unable to absorb essential nutrients. As a result, the brain, nervous system and other vital organs are now being deprived of valuable nutrients which can lead to malnutrition and a number of illnesses. Celiac is not an allergy, and if left untreated can be life-threatening. Celiac can develop at any time in life, from as early as infancy to later in adulthood. If born with a particular set of genes (HLA-DQ2, DQ8), you are susceptible to developing Celiac. It is thought there must be a trigger to turn Celiac on (possibly pregnancy, abdominal surgery, viral or bacterial infection, extreme stress, and also environmental). Once triggered, Celiac is a life-long condition and is presently incurable. Strict adherence to a gluten-free diet is the only treatment and there are no medications currently available. For the majority of people, once gluten is removed from the diet, the villi will heal, anywhere from two months to two years, depending on the severity of the initial damage.
On the bright side, once living a healthy gluten-free lifestyle, individuals who have suffered with debilitating symptoms possibly for years, will finally experience improved health and overall well-being! Most will begin to feel better after just a few weeks of eliminating gluten. Additionally, there is medical research currently underway world-wide – in the US, Finland, Britain, Australia & elsewhere – which in the near future may assist in the treatment of Celiac (see On the Horizon ).
*A multidisciplinary task force of international physicians recently (2/2012) defined Celiac Disease (to be used as a standard among medical professionals) as follows: Celiac Disease is “a chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals’. Classical CD was defined as ‘CD presenting with signs and symptoms of malabsorption. Diarrhoea, steatorrhoea, weight loss or growth failure is required.’ ‘Gluten-related disorders’ is the suggested umbrella term for all diseases triggered by gluten”
Gluten-Sensitivity is different from Celiac – it is not an auto-immune disease. Research has indicated an individual may be sensitive to gluten and experience similar gastrointestinal issues, but without intestinal damage. According to the University of Maryland School of Medicine’s Celiac Research Center, Gluten Sensitivity may affect 6 to 7 percent of the population, as compared to the 1 percent population of Celiacs. For more information on Gluten Sensitivity view the following links related to research conducted by Dr. Alessio Fasano of the Celiac Research Center: http://somvweb.som.umaryland.edu/absolutenm/templates/?a=1474&z=41 ; http://www.biomedcentral.com/content/pdf/1741-7015-9-23.pdf;
Note: Though a gluten-free diet can benefit those with Gluten-Sensitivity, it is strongly recommended not to commence the diet, until Celiac has been ruled out.
A wheat allergy is a food allergy and not an auto-immune disease. No intestinal damage occurs if someone with a wheat allergy consumes gluten. As with any food allergy, symptoms may vary from mild to life-threatening. For more information on wheat allergy, please visit the Mayo Clinic’s website: http://www.mayoclinic.com/health/wheat-allergy/DS01002
[All medical data noted in Celiac 101 sections was compiled after extensive research was conducted on the various subjects noted by way of articles, lectures, medical abstracts, and leading celiac research centers' informational websites. CeliacCorner is not a medical institution]